beta-Estradiol, analytical standard

Code: E1132-1VL D2-231

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty b...


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OVERVIEW

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

Packaging

1 vial in poly bottle

Supplied in amber screw-cap vials

SPECIFICATIONS
application(s)pharmaceutical
Gene Informationhuman ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), GPER(2852), SERPINA6(866)mouse ... Esr1(13982), Esr2(13983), Esrra(26379)rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775)
gradeanalytical standard
InChI keyVOXZDWNPVJITMN-ZBRFXRBCSA-N
InChI1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
mp176-180 °C (lit.)
packagingvial of 250 mg
Quality Level200
SMILES stringO[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
technique(s)HPLC: suitable, gas chromatography (GC): suitable
DOCUMENTS
RANGE
ATTRIBUTES
Cas Number50-28-2
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